Nad+ Safety Information

What Is This Medication?

NAD+ (nicotinamide adenine dinucleotide) is a coenzyme found in every cell of the body that plays a critical role in cellular energy production, DNA repair, and metabolic function. NAD+ levels naturally decline with age, and supplementation aims to restore these levels to support cellular health. NAD+ therapy is used to support cognitive function, mental clarity, energy levels, and overall cellular vitality. It may also play a role in healthy aging by supporting the body's natural repair processes.

Who Should Consider This Treatment?

NAD+ therapy may be appropriate for adults experiencing age-related decline in energy, cognitive function, or overall vitality. It is often sought by individuals looking to support their body's cellular health and recovery processes. Your healthcare provider will review your health history, current medications, and wellness goals to determine whether NAD+ therapy is a suitable option for you.

Who Should Not Use This Medication?

Do not use NAD+ therapy if you have any of the following:

• A known hypersensitivity or allergy to NAD+ or any of its components
• Are currently pregnant or planning to become pregnant
• Are currently breastfeeding

Because research on NAD+ supplementation is still evolving, your provider will carefully evaluate your candidacy before prescribing this treatment.

Warnings and Precautions

• NAD+ therapy should be administered under the supervision of a licensed healthcare provider. Do not self-administer without proper training and guidance.
• If you have a history of liver disease, kidney disease, or any chronic medical condition, inform your provider before starting treatment.
• Injection should be administered slowly to reduce the likelihood of flushing, chest tightness, or nausea.
• Monitor for signs of allergic reaction during and after each administration, especially during initial treatments.
• Stay well-hydrated before and after NAD+ injections to support your body's response to the treatment.

Common Side Effects

The most commonly reported side effects include:

• Injection site reactions (redness, swelling, discomfort)
• Nausea
• Headache
• Flushing or warmth sensation
• Dizziness or lightheadedness
• Chest tightness (usually transient during infusion)
• Mild fatigue after treatment

These side effects are generally mild and temporary, typically resolving within a few hours of treatment. Slower administration rates can help reduce discomfort during the injection process.

Serious Side Effects

While rare, seek immediate medical attention if you experience any of the following:

• Severe allergic reaction: rash, hives, swelling of the face, lips, tongue, or throat, difficulty breathing, or rapid heartbeat
• Persistent chest pain or tightness that does not resolve after the injection is complete
• Severe or prolonged nausea, vomiting, or abdominal discomfort

Drug Interactions

There are limited known drug interactions with NAD+ therapy. However, it is important to disclose all medications you are currently taking to your healthcare provider, including prescription drugs, over-the-counter medicines, vitamins, herbal supplements, and any other treatments. Your provider will evaluate potential interactions based on your complete medication profile and adjust your treatment plan accordingly.

Before Starting Treatment

Before beginning NAD+ therapy, inform your healthcare provider if you:

• Have liver or kidney disease
• Have a history of heart disease or cardiovascular issues
• Have any active infections
• Have a history of allergic reactions to injectable medications
• Are pregnant, planning to become pregnant, or breastfeeding
• Are taking any blood thinners or anticoagulants
• Have any autoimmune conditions

How to Use This Medication

NAD+ is administered via subcutaneous injection. Your provider will determine the appropriate dose and frequency based on your individual health profile and treatment goals. Treatment protocols typically involve an initial loading phase followed by a maintenance schedule. Follow your provider's instructions carefully regarding injection technique, site rotation, and dosing frequency. Store the medication as directed by the pharmacy, typically refrigerated. Do not use if the solution appears cloudy, discolored, or contains visible particles.